340B TPA for covered entities: hospitals, FQHCs, clinics and health systems
Aventi Health is an independent, founder-owned 340B third-party administrator (TPA) for hospitals, health systems, FQHCs and clinics. We run contract pharmacy, split billing and specialty pharmacy on one platform, keep your program audit-ready, and prepare you for 2027 340B rebate submissions.
Customers in 30+ U.S. states, 300+ covered entities, and a 10,000+ pharmacy network.
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Who Aventi serves
Hospitals and health systems
Disproportionate share and other hospitals with contract pharmacy programs, mixed-use areas or in-house pharmacies. Aventi runs contract pharmacy and split billing together so purchasing and dispensing stay tied.
FQHCs and community health centers
Health centers that need claim capture across the pharmacies their patients actually use, with transparent, contingency-based pricing.
Clinics and specialty providers
Clinics and specialty practices whose patients fill high-cost specialty and infusion medications, where the biggest 340B opportunities sit.
Other 340B covered entities
Any HRSA-registered 340B covered entity that wants an independent TPA that answers to providers, not to a wholesaler, PBM or pharmacy chain.
340B TPA services for covered entities
Contract pharmacy administration
Real-time claim capture across a 10,000+ pharmacy network, precise eligibility matching, referral capture beyond your walls, and a dedicated account manager.
Split billing
Automatic separation of drug purchases by patient eligibility across 340B, GPO and WAC accounts, compliant with the GPO Prohibition, with no end-of-month true-ups.
340B rebate model readiness for 2027
Beacon-ready pharmacy and medical rebate submissions with conforming claim units, plus in-house pharmacy medical claims submissions to Beacon today.
Compliance and audit readiness
Every claim stays audit-ready. Real-time 340B ESP and Truzo (Kalderos) integration, current manufacturer restriction tracking, Good Faith Inquiry (GFI) tracking and duplicate discount monitoring.
Reporting and analytics
One view of net 340B benefit, claims by status, and savings and fees by pharmacy, with centralized reporting your finance and compliance teams can use.
MFP reconciliation and negative balance tools
Reconciliation does not disappear under a rebate model. Aventi provides MFP reconciliation tools and negative balance management.
Specialty pharmacy: a core Aventi expertise
Specialty and infusion medications are often the highest-value 340B opportunities, and they are where many TPAs struggle. Specialty pharmacy is a core Aventi expertise. We have exclusive integrations and a gateway with BioPlus, Accredo and Optum, plus many other specialty pharmacies, so specialty dispense data flows into your 340B program instead of getting lost.



- …and many other specialty pharmacies
- Exclusive integrations and a gateway with BioPlus, Accredo and Optum
- Specialty referral and claims data brought into one platform for eligibility matching and audit-ready reporting
- Specialty claims included in your 2027 rebate readiness and reporting
Ready for the 2027 340B rebate model
HRSA's 340B Rebate Model Pilot Program starts January 1, 2027, with claims data submitted to Beacon within 45 days of dispense. Aventi prepares and submits pharmacy and medical rebate claims for covered entities. Rebate claim submission is included for Aventi TPA clients and is $750 per covered entity per month for covered entities that use another TPA.
How onboarding works
Step 1: Demo or free 340B assessment
We review your 340B program, pharmacies and goals, and show you the platform.
Step 2: Connect your pharmacies and data feeds
Contract, in-house and specialty pharmacy data connects to Aventi through our pharmacy network, direct integrations and the specialty pharmacy gateway with BioPlus, Accredo, Optum and many other specialty pharmacies, so claims data arrives without manual spreadsheets.
Step 3: Configure your program
We set up eligibility matching, 340B, GPO and WAC account splitting for split billing, and 340B ESP and Truzo connections.
Step 4: Go live with a dedicated account manager
Real-time claim capture, reporting and portal access, with a dedicated account manager as your point of contact.
Step 5: Stay audit-ready and rebate-ready
Ongoing reconciliation, GFI tracking, manufacturer requirement monitoring and rebate claim submission for 2027.
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Trusted by covered entities in 30+ U.S. states
Aventi supports 300+ covered entities across the United States, in 30+ states, with a 10,000+ pharmacy network, so eligible claims are captured wherever your patients fill prescriptions.