Get ready for 340B rebate submissions in 2027.
Today, covered entities generally buy 340B drugs at the discounted 340B price up front. Under a rebate model, the covered entity pays a higher price at purchase, submits claims data showing the drug was 340B-eligible, and receives the difference back as a rebate. Aventi is an independent 340B TPA that helps covered entities prepare and submit that claims data, alongside contract pharmacy and split billing on one platform.
- 1Purchase
The covered entity buys the drug at a non-340B price instead of the 340B price.
- 2Submit
Claims data for eligible dispenses is submitted to show the drug qualified for 340B.
- 3Rebate
Once the data is validated, the manufacturer pays the 340B discount back as a rebate.
What is the 340B rebate model?
Purchase
The covered entity buys the drug at a non-340B price instead of the 340B price.
Submit
Claims data for eligible dispenses is submitted to show the drug qualified for 340B.
Rebate
Once the data is validated, the manufacturer pays the 340B discount back as a rebate.
The rebate model changes when and how the 340B discount reaches you. It makes accurate, timely claims data central to getting paid.
Why covered entities need to be ready for 2027
HRSA's revised 340B rebate pilot proposal has advanced through the federal review process, with a second pilot expected to align with the expansion of the Inflation Reduction Act's Medicare Maximum Fair Price (MFP) program in 2027. Fifteen additional drugs are scheduled to enter the MFP program in 2027, adding to the ten drugs already in the program in 2026.
Beacon, developed by Second Sight Solutions, currently supports Medicare MFP validation and could play a larger role if the HRSA rebate model moves forward. Manufacturers also continue to use 340B ESP and Kalderos TruZo.
Reconciliation will not disappear under the rebate model. Covered entities already juggling multiple manufacturer portals, changing manufacturer requirements, staff capacity constraints and manual MTF claim downloads will need clean, submission-ready claims data.
Final timing and scope depend on HRSA. When the rules change, you hear from us first.
One independent TPA for rebate submissions
Beacon-ready
Built for HRSA's rebate model pilot, ready when it resumes.
Submission-ready claims data
Real-time claim capture and precise eligibility matching keep every claim audit-ready.
340B ESP and Truzo (Kalderos)
Real-time 340B ESP integration and an API connection to Truzo, with automated ESP and TruZo submissions for both contract and in-house pharmacies.
Reconciliation and GFI tracking
Good Faith Inquiries submitted and tracked in one view, plus MFP reconciliation tools, negative balance management and duplicate discount monitoring.
One platform
Contract pharmacy and split billing run on a single foundational system, with centralized reporting and analytics.
Independent, contingency-only
Founder-owned with no conflicting incentives, transparent contingency-only pricing, and a dedicated account manager.