Aventi vs Wellpartner: a 340B TPA alternative outside CVS Health
Wellpartner is CVS Health's 340B third-party administrator. It was acquired by CVS Health in December 2017 and says it works with more pharmacies than any other 340B administrator, with a network of over 60,000 CVS and non-CVS locations.[1][5] Many covered entities are looking at their Wellpartner relationship right now: CVS is replacing its existing 340B agreements, including Wellpartner's, with new ones that must be signed by December 1, 2026,[16] and the 2027 340B rebate model starts January 1. This page lays out the facts, the questions to ask, and your options, including keeping Wellpartner and using Aventi only for rebate claims.
Aventi Health is an independent, founder-owned 340B TPA serving 300 covered entities, 24 of them hospitals.
Last updated: . Every statement about Wellpartner and CVS links to a public source.
Three dates for Wellpartner clients
Two contract dates from CVS and one regulatory date from HRSA all land in the same six weeks.
December 1, 2026
Deadline to sign CVS's new 340B agreements for them to take effect January 1, 2027, according to Frier Levitt. The new agreements cover Wellpartner, CVS contract pharmacies, Caremark and CVS specialty pharmacies.[16]
December 31, 2026
Existing CVS 340B agreements executed before July 1 terminate, according to Frier Levitt.[16]
January 1, 2027
New CVS agreements take effect, and HRSA's 340B Rebate Model Pilot starts. Rebate claims are due within 45 calendar days of dispense.[16][19]
Frier Levitt represents hospitals in lawsuits against CVS and describes the new agreements as take-it-or-leave-it, with restricted audit provisions and a mandatory arbitration provision.[17] Some covered entities are signing: in October 2026, Lane County, Oregon approved a new Wellpartner 340B Administrative Services Agreement and a CVS Pharmacy agreement with terms listed as January 1, 2027 to December 31, 2033.[18] Read your own notice and agreement with your counsel. This page is not legal advice.
One parent company, four roles in your 340B claim
Wellpartner says it is backed by CVS Health, which it calls America's largest health care company. When you use Wellpartner with CVS pharmacies, CVS Health companies can sit on every step of a claim.
340B TPA
Wellpartner
Determines which claims are 340B-eligible after they adjudicate, replenishes inventory and reports savings to the covered entity.[11][13]
Contract pharmacy
CVS Pharmacy
Wellpartner says partnering with CVS retail pharmacies lets covered entities capture more eligible claims and bypass many manufacturers' single pharmacy designation rules.[2]
Specialty pharmacy
CVS Specialty
Dispenses high-cost specialty drugs under contract pharmacy agreements, for a dispensing fee.[13][14]
PBM
Caremark
CVS's pharmacy benefit manager. In the hospitals' lawsuits, Caremark is alleged to have repriced 340B specialty claims after Wellpartner flagged them as eligible.[13]
Sources for ownership: Wellpartner's own timeline and approach pages.[1][2] Aventi has no wholesaler, PBM or pharmacy chain parent.
What hospital lawsuits allege about CVS and Wellpartner
On May 21, 2026, hospital systems including members of Mount Sinai, the University of Kansas Health System and University of Michigan Health filed federal lawsuits against CVS Health, CaremarkPCS, Caremark (CVS Specialty) and Wellpartner. They allege the companies retained about $250 million of their 340B savings from 2020 to 2025.[13][14]
The complaints allege that specialty claims were first paid at standard network rates, and that after Wellpartner identified a claim as 340B-eligible, Caremark paid CVS Specialty a lower rate and the lower amount was reported to the hospital, with the difference retained.[13][14] In October 2026, the University of Kentucky filed a similar suit alleging more than $41 million in diverted 340B savings.[15]
These are allegations in pending cases. A CVS Health spokesperson told Fierce Healthcare the company does not comment on matters subject to ongoing litigation.[13] Whatever the outcome, the cases raise questions any Wellpartner client can put to CVS before signing a new agreement:
- Will we get claim-level data showing the reimbursement originally paid on each 340B claim, not just the amount remitted to us?
- What audit rights over Wellpartner, CVS Pharmacy, CVS Specialty and Caremark records do we keep under the new agreements, and how are disputes resolved?
- How are specialty claims priced once they are flagged as 340B-eligible, and is any spread retained by a CVS company?
- If we leave, what data do we get back (claims, accumulators, Community Benefit Program records, 340B ESP submissions), in what format, and how fast?
At Aventi, you see every claim in the same system we use to qualify it, and we do not own a pharmacy, PBM or wholesaler on the other side of your claims.
Aventi vs Wellpartner, side by side
Wellpartner details come from wellpartner.com, checked November 4, 2026. Where Wellpartner has not published something, we say so.
| Aventi Health | Wellpartner (CVS Health) | |
|---|---|---|
| Parent company | None: independent and founder-owned | CVS Health, since December 2017[1] |
| Scale | 300 covered entities, 24 of them hospitals | Says it generates over $2 billion in annual savings for clients; does not publish a client count[3] |
| Pharmacy network | 10,000+ pharmacies, with specialty integrations and a gateway with BioPlus, Accredo, Optum and many others | Over 60,000 CVS and non-CVS specialty and retail locations[5] |
| Contract pharmacy | Real-time claim capture and purchase splitting, so no end-of-month true-ups | 340B Confident, with customizable carve-in and carve-out rules[5] |
| Split billing and in-house pharmacy | Split billing on the same platform as contract pharmacy | 340B Smart (split billing across 340B, GPO and WAC accounts) and 340B Counter (in-house pharmacy inventory)[7][8] |
| Multi-TPA oversight | One rebate submission and reconciliation flow across sites, even if some use another TPA | 340B Compliance analyzes claims across all of a covered entity's TPAs and flags ineligible claims[9] |
| Manufacturer data platforms | Real-time 340B ESP and Truzo (Kalderos) integration | Direct feed to 340B ESP on the client's behalf[6] |
| 2027 rebate model | Beacon-ready for pharmacy and medical rebate submissions; already submits in-house pharmacy medical claims through Beacon | Not described on Wellpartner's public website as of November 4, 2026[4][20] |
| Pricing model | Contingency-based, no true-ups. Rebate module included for Aventi TPA clients. | Says it was the first administrator to offer performance-based pricing (2023); fees not published[1] |
Product names are trademarks of their owners. Spot an error? Email hello@aventihealth.com and we will correct it.
Beyond the claims engine: what else Wellpartner provides
If you are weighing a switch, list which of these you rely on so nothing falls through the cracks.
340B Clarity
Client reporting portal launched in 2014, with claims, carve-in and carve-out, order and invoice views, review of pending encounter and prescription claims, a volume activity dashboard and a compliance checklist.[1][6]
Community Benefit Program
Programs that give uninsured and underinsured patients reduced or no-cost medications at subsidy levels the covered entity sets. Wellpartner says it administers more than $83 million a year in these programs.[4][10]
Audit support
A Client Audit Readiness Profile, simulated HRSA audits based on past audits, a documentation binder, and a member of its audit team on site during an HRSA audit.[11]
In-house technology team
Wellpartner says it has the largest in-house technology team of any 340B administrator, with more than 80 in-house developers, and promises a callback within one business day.[2]
Analytics partnership
Wellpartner has announced a collaboration with Plenful to review eligible claims in Wellpartner data, flag exceptions and identify misclassified claims.[12]
340B Calibrate
Announced in 2022 as a program excellence offering to help covered entities improve oversight and grow their 340B programs.[1]
Wellpartner and the 340B rebate pilot: what is public so far
HRSA's 340B Rebate Model Pilot starts January 1, 2027. Ten manufacturers have approved plans, all using the Beacon platform. Covered entities keep buying selected drugs through their 340B wholesaler account, submit claims data within 45 calendar days of dispense, and manufacturers must pay or deny within 10 calendar days of a complete submission.[19]
As of November 4, 2026, Wellpartner's solutions, approach and FAQ pages do not mention the rebate pilot or Beacon.[2][4][11] Wellpartner does say it can submit data directly to 340B ESP on a client's behalf.[6] That may change, so ask Wellpartner three things in writing: who submits your pharmacy and medical rebate claims to Beacon, how denials and good faith inquiries are tracked, and how rebate payments are reconciled against your 340B savings reports.
Aventi qualifies rebate claims, submits them to Beacon and reconciles payments in the same system that runs your eligibility, split billing and contract pharmacy claims. Read about handling 340B rebate denials and rebate reconciliation.
Three paths for Wellpartner clients before December 1
You do not have to decide everything at once. Each path keeps 2027 rebate claims covered.
Keep Wellpartner, add Aventi for rebates
Sign CVS's new agreements if they work for you, and name Aventi your designated third party for 2027 rebate claims. Contact us for pricing. No TPA switch required.
Run two TPAs during a transition
Many covered entities already use more than one administrator, a setup Wellpartner itself addresses in its FAQ. Move some sites or pharmacies to Aventi first and keep one rebate flow across both.
Move your TPA services to Aventi
Bring contract pharmacy and split billing to an independent TPA with contingency-based pricing. The rebate module is included for Aventi TPA clients.
Wellpartner's FAQ discusses covered entities with multiple administrators using different claims qualification processes.[11]
Switching from Wellpartner to Aventi: a checklist
Step 1: Read the termination notice and dates
Confirm when your current Wellpartner and CVS agreements end and what notice they require, so a TPA change and the December 31 termination line up.[16]
Step 2: Export your Clarity data
Download claims, carve-in and carve-out settings, orders, invoices and financial reports from 340B Clarity before access ends.[6]
Step 3: Rebuild your Community Benefit Program
Document patient eligibility tiers and subsidy levels so patients on reduced or no-cost medications are not interrupted.[10]
Aventi runs onboarding with you and can submit rebate claims while you are still on Wellpartner. See the demo to walk through it.
Wellpartner vs Aventi: frequently asked questions
Sources
- Wellpartner, About Us (company timeline) — https://www.wellpartner.com/about-us.html
- Wellpartner, Our Approach — https://www.wellpartner.com/about-us/our-approach.html
- Wellpartner, Home — https://www.wellpartner.com/
- Wellpartner, 340B Solutions — https://www.wellpartner.com/340b-solutions.html
- Wellpartner, 340B Confident — https://www.wellpartner.com/340b-solutions/340b-confident.html
- Wellpartner, 340B Clarity — https://www.wellpartner.com/340b-solutions/340b-clarity.html
- Wellpartner, 340B Smart — https://www.wellpartner.com/340b-solutions/340b-smart.html
- Wellpartner, 340B Counter — https://www.wellpartner.com/340b-solutions/340b-counter.html
- Wellpartner, 340B Compliance — https://www.wellpartner.com/340b-solutions/340b-compliance.html
- Wellpartner, Community Benefit Program — https://www.wellpartner.com/340b-solutions/community-benefit-program.html
- Wellpartner, 340B FAQs — https://www.wellpartner.com/resources/340b-faqs.html
- Wellpartner, Wellpartner and Plenful (Expert Insights) — https://www.wellpartner.com/resources/expert-insights/wp-plenful.html
- Fierce Healthcare, "Hospitals allege CVS Health subsidiaries pocketed 340B savings" (May 21, 2026) — https://www.fiercehealthcare.com/payers/hospitals-allege-contracted-cvs-health-subsidiaries-pocketed-their-340b-savings
- AJMC, "CVS Health Sued Over Alleged Scheme to Siphon 340B Drug Program Savings" (May 21, 2026) — https://www.ajmc.com/view/cvs-health-sued-over-alleged-scheme-to-siphon-340b-drug-program-savings
- Becker's Hospital Review, "University of Kentucky sues CVS over alleged $41M 340B scheme" — https://www.beckershospitalreview.com/pharmacy/university-of-kentucky-sues-cvs-over-alleged-41m-340b-scheme/
- Frier Levitt (counsel for the plaintiff hospitals), "CVS to Replace 340B Agreements Amid Ongoing Litigation" (September 24, 2026) — https://www.frierlevitt.com/news/cvs-new-340b-agreements-contract-pharmacy/
- Frier Levitt (counsel for the plaintiff hospitals), "CVS 340B Contracts and Termination Notices: What to Know" (September 28, 2026) — https://www.frierlevitt.com/articles/cvs-340b-contracts-termination-notices/
- Lane County (Oregon) Board of Commissioners, Order No. 26-10-13-03 (October 13, 2026) — https://cdnsm5-hosted.civiclive.com/UserFiles/Servers/Server_3585797/File/Government/BCC/2026/2026_ORDERS/101326/Order%2026-10-13-03.pdf
- HRSA, 340B Rebate Model Pilot Program — https://www.hrsa.gov/opa/340b-model-pilot-program
- Aventi Health, 340B Rebate Model — https://aventihealth.com/340b-rebate-model
Accessed November 4, 2026.
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